Amylin hormone
نویسندگان
چکیده
منابع مشابه
The satiating hormone amylin enhances neurogenesis in the area postrema of adult rats
OBJECTIVE Adult neurogenesis in the subgranular zone and subventricular zone is generally accepted, but its existence in other brain areas is still controversial. Circumventricular organs, such as the area postrema (AP) have recently been described as potential neurogenic niches in the adult brain. The AP is the major site of action of the satiating hormone amylin. Amylin has been shown to prom...
متن کاملHistamine H1 receptors mediate the anorectic action of the pancreatic hormone amylin.
We investigated the role of histamine H1 receptors in mediating the anorectic effect of intraperitoneally injected amylin (5 and 20 microg/kg), the amylin agonist salmon calcitonin (sCT; 10 microg/kg), leptin (1.3 mg/kg), and cholecystokinin (CCK; 20 microg/kg). The experiments were performed with mice lacking functional H1 receptors (H1Rko) and wild-type (WT) controls. The mice were also injec...
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Amylin is a 37-aminoacid pancreatic protein that exerts control over several metabolic events such as glycemia and lacticemia. Amylin has long been shown to induce increases in arterial plasma glucose. We decided to investigate whether amylin plays additional roles in the glucose metabolism. We evaluated glucose homeostasis using whole blood from the tail tip of fasting, conscious, unrestrained...
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Amylin is a peptide that aggregates into species that are toxic to pancreatic beta cells, leading to type II diabetes. This study has for the first time quantified amylin association and dissociation kinetics (association constant (ka ) = 28.7 ± 5.1 L mol-1 s-1 and dissociation constant (kd ) = 2.8 ± 0.6 ×10-4 s-1) using surface plasmon resonance (SPR). Thus far, techniques used for the sizing ...
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Obesity is a chronic disease that shows the most serious global health problems .It relates to the body fat .Obesity is caused by an imbalance between energy intake and expenditure, this balance is regulated by genetic and environmental interactions. Obesity, which is a risk factor for chronic diseases, has become epidemic in the developed countries. Resistance to Leptin hormone is one of the m...
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ژورنال
عنوان ژورنال: Nature
سال: 1989
ISSN: 0028-0836,1476-4687
DOI: 10.1038/340272b0